A validation of the new point of care GeneXpert tropical fever test. To determine systematically the etiology of fevers among acute febrile illness patients attending clinics in different district hospitals of the Mwanza region. And to prospectively acquire Whole Blood specimens collected by Finger Stick and venous blood draw for the development and validation of the Cepheid Xpert® Tropical Fever test.
It is a hospital-based cross-sectional study involving 861 outpatient clients with acute febrile illness attending the clinic at Mwanza District Hospitals with complaints of fever in less than 10 days and have not taken any antibacterial or antiparasitic drugs within the past 3 days. Point of care rapid diagnostic tests will be used for the detection of P. falciparum, typhoid, dengue, chikungunya, and zika for all patients.